The customer-x-pectations.com Vitamin D receptor (VDR) is a nuclear transcriptional regulator of multiple genes. It is pleiotropic results on multiple physiological devices make it a advisable target with regards to investigating disease mechanisms and therapeutic responses. In an in-vitro assay, the FokI CC genotype of VDR showed an improved response to 1, 25-dihydroxyvitamin D3 (VitD3) in contrast to the TT genotype. The in response can be due to the gear expression of varied enzymes linked to hydroxylase activity and the creation of 25-dihydroxyvitamin D3 in the two genotypes.
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